Chemical Loading of Doxorubicin onto Onion DNA and its Medical use

Abstract

A new natural biopolymer was prepared by modifying the structure of the drug Doxorubicin by loading it onto DNA extracted from onions and dotted with Maleic anhydride monomer The goal of this design is to increase effectiveness of the anti-cancer drug known to be used medically, and to reduce the harms and side effects, the use of Doxorubicin may lead to the occurrence of many side effects, such as: cardio toxicity, bone marrow inhibition, and liver damage. It is also characterized by its anti-cancer activity and its status as a natural polypeptide. Its main chain was copolymerized using anhydrous malic acid. Then replace it with the amino drug Doxorubicin. In order to upsurge the drugs life, and release the modified drug with expanded drug action by gradual release with its excellent performance. This new biological polymer was applied to mice, and it gave distinct results. The infected mice were treated and made a complete recovery without secondary damage and without leaving traces. It could be a better drug than Doxorubicin if it was alone, by filling it onto the DNA. In order to gain thermal stability during storage. Compound RA has high selectivity and can be adopted as a drug for cancerous tumors and the option of its use and development, as it gave double distinct results without any effects on living cells.