Evaluation of the Concentrations of Some Hormones and Vitamins in Infertile Women in Dhi Qar Governorate

الملخص

Objective: To evaluate the association between female infertility and the concentrations of estrogen, progesterone, testosterone, prolactin, and vitamin C,E, and D. Methodology: The study initially included 230 women with infertility.Using stratified random sampling,30 women were selected for laboratory analysis:15 with primary infertility and 15 with secondary infertility.Ten apparently healthy women served as controls.Approximately 7 mL of venous blood was collected from each participant during the first week of the menstrual cycle and used to measure all study parameters.Estrogen, progesterone, testosterone, prolactin, and vitamin D were measured using a Cobas e 411 analyzer based on electrochemiluminesce technology, whereas vitamin C and E were measured by ELISA using USCNK kits (China). Results: One-way analysis of variance showed significantly lower estrogen and progesterone concentrations and significantly higher prolactin concentrations in both infertility groups than in the control group (P≤0.05). Estrogen was also significantly lower in the primary infertility group than in the secondary infertility group.Testosterone did not differ significantly among the control group, whereas vitamins C and E showed no significant group differences. Conclusions:Female infertility was associated with altered estrogen, progesterone, prolactin, and vitamin D concentrations. These finding should be interpreted with considerations of body mass index, dietary intake,sun exposure, supplement use, and lifestyle factors.