التقييم المناعي لمرضى التهاب المفاصل الروماتويدي في محافظة بغداد

الملخص

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily affects the joints. Inflammation of the synovium, cartilage, and bone erosion are the most prominent symptoms of RA. The stages of development of this disease are very complex, as synovial cells rupture and form inflammation of the synovium, followed by deterioration of cartilage and bone. Cytokines are proteins that play a crucial role in the onset and progression of disease. This study was conducted at Medical City Hospital in Baghdad. It included 50 blood samples from patients with rheumatoid arthritis (25 males and 25 females), in addition to 30 healthy people (15 males and 15 females) a control group, aged between 10 and 60 years. The levels of Interleukin-2 ( IL-2)  and  Interleukin-6  (IL-6) were measured using enzyme-linked immunosorbent assay (ELISA), and  Hemoglobin Test ( Hb )  ,  White blood cells  (WBC) , Erythrocyte sedimentation rate  (ESR ) , Urea, , sugar  test , Lactate dehydrogenase ( LDH) and Creatinine  were measured for all infected and healthy people. The results showed a significant increase (P<0.05) in all measurements of IL-2, IL-6,  Hb,WBC, ESR, urea, , sugar,  LDH and Creatinine .